In Tokyo, the Nikkei 225 was 0.28 percent lower to 16,785.69 on Friday.

The Topix index closed at 1,616.62, while the Mothers market was higher, ending the session at 732.72 for a gain of 1.7 percent.

The pharmaceuticals sector was mixed.

Chugai Pharmaceutical (TYO: 4519) was 2.6 percent lower to ¥1,897 after it said it would need to extend clinical tests for a new anemia drug, while Daiichi Sankyo (TYO: 4568) gained 4.6 percent to ¥3,450 on the news that the US Food and Drug Administration approved its new blood pressure medication.

House builders were also mixed.

While Daiwa House Industry (TYO: 1925) dropped 0.1 percent to ¥1,499, Sekisui House (TYO: 1928; OTC: SKHSY) was 0.6 percent higher to ¥1,446.

In the real estate sector, Mitsubishi Estate (TYO: 8802) was down 3 percent to ¥3,290.

Consumer lender Takefuji (TYO: 8564) added 5.8 percent to ¥2,280 after it announced a share buy-back.

Camera and copier maker Canon (TYO: 7751; NYSE: CAJ) gained 2.6 percent to ¥6,270 on the possibility that it might also buy back shares.

Construction equipment manufacturer Mitsubishi Heavy Industries (TYO: 7011) was 1.9 percent higher to ¥751 on the announcement that it will supply a Chinese nuclear facility.

Tokyo equities markets were lower on Tuesday as investors worried that dropping commodities prices are signaling a slowdown in the global economy. The Nikkei 225 was 0.5 percent lower to 15,719.34, while the Topix index dropped 0.7 percent to 1,585.98. The Mothers Index of small and mid-caps fell even more sharply, declining by 2.9 percent to 1,272.58.

Commodities-dependent stocks were lower, with Sumitomo Metal Mining down 4.7 percent to ¥1,595 despite revising its full-year prediction higher, while Mitsubishi Materials dropped 4.9 percent to ¥481. In the oil sector, Inpex was 2.2 percent lower to ¥929,000.

New data showing machinery orders were lower than had been expected, released Monday, was still showing an effect as heavy machinery manufacturer Komatsu declined by 4.1 percent to ¥2,090.

Transport, however, saw gains on the session. Among shipping lines, Mitsui OSK Lines was 0.7 percent higher to ¥881. Nippon Yusen added 1.1 percent to ¥720, while smaller peer Kawasaki Kisen was up 1.2 percent to ¥754. Door to door delivery company Yamato Holdings and airline ANA each added 1.3 percent, to ¥1,813 and ¥479 respectively.

In the pharmaceuticals sector, Daiichi Sankyo added 3.9 percent to ¥3,210 on the news that as part of a plan to get rid of all non-core pharma businesses by early next year, it will sell two diagnostics units soon.

The Tokyo finance markets were higher on Wednesday. The Nikkei 225 and the Topix index each added 0.2 percent, to 15,464.29 and 1,569.65 respectively. The Mothers index of small and mid-caps was even higher, gaining 5 percent to 1,277.3.

Oji Paper was 2.1 percent higher to ¥681 after it said it will continue to pursue its hostile takeover bid for Hokuetsu Paper Mills. Hokuetsu gained 3.8 percent to ¥814.

The pharmaceuticals sector was mixed. Takeda added 0.8 percent to ¥7,540 and Daiichi Sankyo was up by 2 percent to ¥3,310. Astellas, however, dropped 1.3 percent to ¥4,510 after higher research expenditures and lower prices on its products led to a decline of 64 percent in quarterly profits.

Export-focused businesses saw share prices fall. Camera and copier maker Canon was 0.9 percent lower to ¥5,400, while Sony declined by 1 percent to ¥5,180. Heavy machinery manufacturer Komatsu fell 1.1 percent to ¥2,275 and industrial robot maker Fanuc ended the session down 2 percent to ¥9,330.

Industrial electronics manufacturer Hitachi dropped 3.5 percent to 693 after it was said that it is being urged to pay more than ¥100 billion to compensate Chubu Electric Power after one of the utility’s nuclear plants shut down because a Hitachi-designed turbine was flawed.

Banks were down on the session. Mizuho Financial fell 0.4 percent to ¥939,000, while Mitsubishi UFJ dropped 0.6 percent to ¥1,556,000 after its quarterly report disappointed investors.

Both the Nikkei 225 and the Topix index saw gains in Tokyo on Monday. The Nikkei added 0.7 percent to 15,456.81, while the Topix was up 0.8 percent to 1,572.01. Both domestic and export-focused sectors saw gains.

Not every sector was up, however. With chances of consolidation in the paper sector decreasing, Oji Paper and Hokuetsu Paper Mills were down on the day. Oji dropped 0.2 percent to ¥665, while Hokuetsu was 1.5 percent lower to ¥790.

The pharmaceuticals sector also saw losses. Astellas dropped 1.3 percent to ¥4,560. Chugai and Daiichi Sankyo fell by 1.9 percent each, with Chugai closing at ¥2,365 and Daiichi Sankyo ending the session at ¥3,150. Takeda was 2.4 percent lower to ¥7,400 on the news that a new cancer drug that it is developing has not shown the usefulness that had been hoped for.

The properties sector showed gains in anticipation of land prices having gone up when the National Tax Agency reports new data. Mitsubishi Estate added 1.9 percent to ¥2,375, while Mitsui Fudosan, Japan’s biggest mortgage lender, gained 2.1 percent to ¥2,435 and NTT Urban Development was 4.1 percent higher to ¥864,000.

Technology-related companies also saw advances on the day. Hitachi and Toshiba each gained 1.4 percent to ¥734 and ¥741 respectively. Elpida Memory added 2.2 percent to ¥4,590, while computer maker Fujitsu was up by 3.6 percent to ¥889.

Declines in stocks related to commodities sent the Tokyo equities markets lower on Tuesday. The Nikkei 225 dropped 1.4 percent to 14,648.41, while the Topix index declined by 1.1 percent to 1,510.32. The Mother’s index of small and mid-cap stocks was also down, by 2.1 percent.

Transport-related stocks were down on the day. Japan’s largest airline, JAL, lost 2 percent to ¥299 on news of a possible strike on Wednesday that could disrupt flight schedules. Railways were down as well. Hankyu lost 4 percent to ¥535 after it said it had paid more than it intended to for Hanshin Electric Railway, which was down 5.4 percent to ¥848.

Commodities-related stocks fell as concerns continued about the state of the US economy as well as in reaction to Monday’s news that China’s central bank has begun a program to decrease lending, which could see demand for commodities there decline. Sumitomo Metal Mining lost 4.5 percent to ¥1,253, while Mitsui Mining & Smelting dropped 3.8 percent to ¥638.

Falling crude oil prices sent shares in oil-related companies lower. Nippon Oil declined by 0.9 percent to ¥799, while refiner and distributor Cosmo was down 2 percent to ¥502 and Inpex fell 3 percent to ¥890,000.

Glassmakers were also lower on the day. Asahi Glass, Japan’ largest, was down 2.3 percent to ¥1,417, while Nippon Sheet Glass dropped 4.1 percent to ¥615 as investors showed their displeasure that it now owns UK glassmaker Pilkington.

Advances were seen in the pharmaceutical sector, where Daiichi Sankyo added 1.4 percent to ¥2,930, as well as in restaurants, where Yoshinoya D&C added 2.2 percent to ¥229,000 on the prospect that US beef imports might resume soon.

The Tokyo equities markets were lower on Monday as export-reliant sectors saw declines on the news that China’s central bank is cutting back on lending. The announcement spurred worries that China’s economy is slowing down. The Topix index was also hurt by declines in the banking sector.

The Nikkei 225 was 0.1 percent lower to 14,860.35, while the Topix dropped 0.5 percent to 1,527.66. Meanwhile, the Mothers index of small and mid-cap stocks closed flat at 1,462.71.

Among companies hit by the news from China were smelter Mitsubishi Materials, which dropped 3 percent to ¥458 and construction machinery manufacturer Komatsu, down 3.5 percent to ¥2,075.

The electrical machinery sector dropped 0.5 percent as a sector. Among electronics companies, Hitachi was down 1.1 percent to ¥743, while Sony dropped 1.6 percent to ¥4,860. In the semiconductor sector, Advantest lost 2.6 percent to ¥10,750.

Among banks, Mizuho lost 1.9 percent to ¥875,000, while Mitsubishi UFJ declined by 2 percent to ¥1,460,000.

Pharmaceuticals and seafood companies, however, saw gains on the day. Strong export sales in the seafood sector saw Nippon Suisan add 3.1 percent to ¥589 and Maruha gain 3.5 percent to ¥325.

The pharmaceuticals sector was up 2.3 percent as a whole. Takeda added 1.7 percent to ¥6,730, Chugai was up 3.4 percent to ¥2,280, and Daiichi Sankyo gained 6.1 percent to ¥2,890.

Ishikawa Seisakusho, which manufactures defence products in addition to textiles, added 17.7 percent on the day to ¥166 as suspicions rose that North Korea is preparing to test a missile in the near future.

Equities markets in Tokyo saw substantial gains on Friday in both domestic and export-focused sectors. The Nikkei 225 ended the day 2.8 percent higher at 14,879.34, while the Topix index added 3.3 percent to 1,534.71.

The steel sector added 4.7 percent as a whole on increased demand around the world. Nippon Steel was up 3.9 percent to ¥405, while Kobe Steel and Sumitomo Metal Mining each advanced by 4.6 percent to ¥339 and ¥1,330 respectively.

Banks were up 4.3 percent as a sector on the expectation that interest rates will rise in July. Mitsubishi UFJ gained 4.2 percent to ¥1,490,000, while Mizuho Financial advanced by 4.9 percent to ¥892,000.

Mitsui Fudosan was up 3.9 percent to ¥2,295 and Daiwa House added 5.1 percent to ¥1,773 as the real estate sector as a whole added 4.1 percent.

Retail saw gains as well. Seven & I advanced by 2.2 percent to ¥3,710, while Aeon gained 4.4 percent to ¥2,500.

The pharmaceuticals sector was up, but only by 0.8 percent and results were mixed for companies within the sector. Astellas Pharmaceuticals added 1 percent to ¥4,020, but Chugai and Daiichi Sankyo lost share value, by 0.9 percent to ¥2,205 and by 2 percent to ¥2,725 respectively.